Pandemics & outbreaks: the mental health side
An outbreak touches far more than our bodies. Whatever you carried through it, your feelings make sense, and most people find their way back.
By the numbers
What research tells us about COVID-19 and mental health.
World
United States
Young people
How outbreaks affect the mind
Why a disease outbreak weighs on mental health, even for people who never get sick.
A pandemic is a disease outbreak that spreads across many countries. The World Health Organization declared COVID-19 a pandemic on March 11, 2020. In May 2023, WHO said it was no longer a global health emergency, but an ongoing health issue.
WHO names many reasons mental health suffered: isolation, loneliness, fear of infection, illness and death of loved ones, grief, and money worries. Exhausted health workers were hit hard too.
Researchers who study pandemic stress found that worry tends to cluster into a few common forms. Many people feel more than one.
Read more
Fear of infection and of possibly contaminated surfaces was one of the most common pandemic worries researchers measured.
Some caution is healthy and protective. It becomes heavy when it takes over your day or keeps growing even when the risk is low.
Read more
Fears about the economic effects of a pandemic formed their own cluster of stress in research.
SAMHSA lists time off work, lost income and job security, and trouble getting groceries and basics among the most common worries during an outbreak.
Read more
Compulsive checking and reassurance-seeking about pandemic threats was another pattern researchers found.
Checking can calm worry for a moment, but often makes it come back stronger. SAMHSA suggests staying up to date while limiting news, since around-the-clock coverage tends to raise anxiety.
Read more
Researchers also measured fear of outsiders who might spread infection. This kind of fear can turn into unfair blame of whole groups.
The section “Stigma, blame & fear of others” in this guide looks at how that harms people and what helps.
Read more
Some people had nightmares and intrusive thoughts about the pandemic. These traumatic stress reactions were another cluster in research.
SAMHSA advises reaching out to a clinical provider if reactions like these last 2 to 4 weeks or more.
Fear of getting sick, and of making others sick
Worry for yourself, your family, and the people you might expose.
During an outbreak, worry often reaches beyond your own health. SAMHSA lists fear about the health of people you may have exposed, and fear that friends or family will resent you if they have to stay home because of you.
Feeling watched can add stress too. Monitoring yourself for symptoms, or being monitored by others, is a common source of anxiety.
Read more
Worrying about people who could get very sick is natural. It shows how much you care.
SAMHSA also names worry about caring for children or others who depend on you as a common outbreak stress.
Read more
Infectious illness spreads in ways no one can fully control. Getting sick, or passing it on, is not a moral failing.
If guilt stays heavy, especially after a loss, the “Survivor’s guilt” guide in this app may help.
Read more
SAMHSA lists anger about being exposed through other people’s negligence among typical reactions.
Anger is a normal signal that something felt unfair. Naming it, moving your body, or talking it through can help it pass without harming relationships.
Read more
Media coverage can make the danger feel closer than it is. SAMHSA suggests looking to credible sources and avoiding news 24/7.
A WHO review found misinformation in up to 28.8% of social media posts about COVID-19.
Isolation, loneliness & lost routines
What happens when the usual ways we connect suddenly close.
Outbreaks can close schools, workplaces, gyms, places of worship and events. SAMHSA notes that social distancing is meant to slow the spread, but it can leave people feeling cut off from the world and from loved ones.
A review of 34 studies with over 215,000 people found loneliness rose during the COVID-19 pandemic compared with before. The increase was small on average, but it was real.
Read more
WHO names loneliness and isolation as key reasons mental health worsened during COVID-19. Isolation limited people’s ability to work, lean on loved ones and take part in community life.
Read more
A major review of quarantine research found boredom and frustration were common stressors, along with longer time apart.
SAMHSA lists boredom and frustration about not being able to work or do daily activities among typical reactions.
Read more
The National Child Traumatic Stress Network notes that outbreaks can disrupt routines and important life events for families.
Missing these moments is a real loss. It’s okay to grieve them, even if others had it harder.
Read more
One year into the COVID-19 pandemic, 2 in 3 U.S. adults said they were sleeping more or less than they wanted.
Grief when goodbyes couldn’t happen
Losing people, and losing the usual ways to mourn them.
Pandemics bring loss on a huge scale. Researchers estimate that each COVID-19 death in the U.S. leaves about nine close relatives grieving.
A review of 28 studies found that bereaved families faced extra pain: not being present in final moments, being left out of care, changed funerals, and weaker support from their communities. It also found many signs of resilience and coping.
Read more
Being absent during a loved one’s final moments was one of the hardest parts of pandemic loss for many families.
If you couldn’t be there, it was not because you didn’t love them. Writing a letter, recording a message, or sharing memories can help say what was left unsaid.
Read more
A review of research on funerals found the benefit of rituals depends on whether people can shape them and say goodbye in a way that feels meaningful to them.
That means it’s never too late. Some families hold a memorial, plant a tree, or mark an anniversary once it feels right.
Read more
From March 2020 to April 2021, an estimated 1.1 million children worldwide lost a parent or custodial grandparent, and over 1.5 million lost a primary or secondary caregiver.
The researchers call this a “hidden pandemic” and say psychosocial and economic support can help families care for these children.
Read more
In one Dutch study, grief levels a year or more after a COVID-19 loss were similar to grief after other natural deaths. Sudden, unnatural losses tended to bring heavier early grief.
Frontline and essential workers
The strain on people who kept caring, cleaning, stocking and delivering.
Healthcare workers stood at the front of the pandemic. WHO says exhaustion among health workers was a major trigger for serious distress.
A 2020 review of 13 studies with over 33,000 healthcare workers found about 23% reported anxiety, about 23% reported depression, and nearly 39% had trouble sleeping. Nurses and women reported higher rates.
Read more
Early research found many healthcare workers struggled with mood and sleep during the outbreak, and called for ways to protect their mental health.
Read more
In 2021, U.S. essential workers were more than twice as likely as other workers to have received mental health care since the pandemic began (34% vs 12%).
Their work kept communities running, often with more exposure and less choice. Their stress deserves recognition too.
Read more
Nearly half of U.S. parents (48%) said their stress had increased since before the pandemic. Among parents whose children were still learning from home, it was 62%.
Who was hit hardest
An outbreak doesn’t land on everyone the same way.
WHO found the pandemic’s mental health effects were uneven. Some groups carried far more of the weight.
Read more
WHO says young people were especially affected and at higher risk of self-harm.
In 2021, 37% of U.S. high school students said their mental health was poor most of the time or always during the pandemic.
Read more
WHO says women were more severely affected than men.
A review of 134 groups of people followed over time found small worsening of anxiety, depression and general mental health among women in particular.
Read more
WHO says people with physical health conditions were more likely to develop symptoms of mental health conditions.
A review of 65 studies also found the early rise in symptoms was most pronounced among people with physical health conditions.
Read more
WHO reports that mental health services were among the most disrupted of all essential health services during much of the pandemic.
WHO also notes people with existing mental health conditions, especially severe ones, were more likely to become very ill if infected.
Read more
A review of 18 studies found reported domestic violence rose after stay-at-home and lockdown orders.
Read more
WHO lists the illness and death of loved ones, and grief after bereavement, among the main causes of worse mental health during COVID-19.
The section “Grief when goodbyes couldn’t happen” in this guide covers this more.
Stigma, blame & fear of others
How fear can turn into unfair treatment, and how to push back.
WHO warns that outbreaks can bring social stigma. People may be labelled, stereotyped or treated differently because of a perceived link to the disease.
Stigma can land on people who were sick, their families and caregivers, and on people who simply share a background with a group that gets blamed.
Read more
WHO notes COVID-19 led to discrimination against people of certain ethnic backgrounds.
In a 2020 survey, 31% of Asian American adults said they had faced slurs or jokes about their race since the outbreak, and 26% said they had feared being threatened or attacked.
Read more
SAMHSA notes that people who were isolated because of illness may feel sad or angry when others still fear catching it from them, even after they are no longer contagious.
SAMHSA says learning and sharing accurate information about the real risk often calms these fears and helps people reconnect.
Read more
WHO says stigma can reach anyone seen as having been in contact with the virus.
People who care for the sick deserve support, not suspicion.
Small ways to push back on stigma
- Check in on neighbours who were sick or are recovering
- Gently correct rumours with facts from trusted health sources
- Say “people who have the illness” rather than using labels
- Speak up, or report it, when you see harassment, if it is safe to do so
- Talk about an illness by its proper name, not a place or group
What research after COVID-19 found
A real rise in distress, and a lot of quiet resilience.
Large modelling studies found a real rise in anxiety and depression worldwide in 2020. Places hit hardest by infections and by restrictions on movement saw the biggest increases.
Studies that followed the same people over time tell a more hopeful story. A review of 65 such studies found a small rise in symptoms in March–April 2020 that faded to near pre-pandemic levels by mid-2020 for most groups.
Read more
A 2023 review of 134 groups followed before and during the pandemic found most changes in anxiety, depression and general mental health were close to zero. Depression worsened only slightly.
Averages can hide people who struggled a lot. But they also show how much resilience people have.
Read more
In the review of 65 studies, increases in depression and mood symptoms tended to be larger and were still raised in May–July 2020.
Women, young people and people with health conditions were more likely to feel lasting effects.
Read more
WHO found that by the end of 2021, mental health services had improved somewhat, but many people still couldn’t get care. Many turned to online support.
In early 2021, 47% of U.S. adults said they had delayed or canceled health care.
Read more
The CDC describes Long COVID as a wide range of symptoms that can last months or years after infection. These can include fatigue, “brain fog”, sleep problems, depression or anxiety.
Symptoms can come and go, and often get worse after physical or mental effort.
Read more
Among U.S. high school students in 2021, those who felt close to people at school were far less likely to report poor mental health (28% vs 45%) or persistent sadness (35% vs 53%).
How community helps
Neighbours, friends and groups that help everyone get through.
SAMHSA calls reaching out to people you trust one of the best ways to ease anxiety, low mood, loneliness and boredom during an outbreak.
CDC researchers found connection, both in person and online, was linked with better mental health for teens. They suggest building connection with family, school and community during and after a pandemic.
Ways to support each other during an outbreak
- Checking in on older or isolated neighbours by phone or at the door
- Faith and community groups meeting online or outdoors
- Grocery and errand runs for people who can’t go out
- Holding memorials once it is safe to gather
- Sharing reliable information instead of rumours
Read more
- Ask how they are really doing, and listen without rushing to fix
- Offer something specific, like a call each Sunday or dropping off food
- Remember hard dates, like the anniversary of a loss
- Share helplines gently if they seem overwhelmed
Read more
WHO’s guidance during COVID-19 encouraged people to support neighbours and others in their community.
Research on quarantine also found that seeing it as protecting others, rather than only as a rule, could make it easier to bear.
When and where to get help
Signs it’s time to reach out, and free places to start.
Reach out to a clinical provider or therapist if…
- Alcohol or drugs have become a way to cope
- Daily tasks, work or school feel impossible to keep up with
- Fear, sadness or worry lasts 2 to 4 weeks or more
- Grief still feels unbearable many months after a loss
- Sleeping or eating is off most days
- Thoughts of hurting yourself or someone else come up
The Disaster Distress Helpline supports anyone in the U.S. and its territories struggling with a disaster, including infectious disease outbreaks like COVID-19. Call or text 1-800-985-5990, free and open 24/7. Press 2 for Spanish; interpreters are available in over 100 languages.
Deaf and hard of hearing people can reach the Disaster Distress Helpline at the same number through their preferred relay service.
Not safe at home? The National Domestic Violence Hotline is free and open 24/7: call 1-800-799-7233 or text START to 88788.
Outside the U.S.? Find A Helpline (findahelpline.com) lists free, confidential helplines by country.
📝 Worksheets for this guide
Fill these in privately in the app. Your answers stay on your phone.
Sources
- World Health Organization (WHO) (2022). COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide
- The Lancet (peer-reviewed) (2021). Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic (COVID-19 Mental Disorders Collaborators)
- The Lancet (peer-reviewed) (2021). Global minimum estimates of children affected by COVID-19-associated orphanhood and deaths of caregivers: a modelling study (Hillis SD, et al.)
- Brain, Behavior, and Immunity (peer-reviewed) (2020). Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis (Pappa S, et al.)
- Proceedings of the National Academy of Sciences (PNAS, peer-reviewed) (2020). Tracking the reach of COVID-19 kin loss with a bereavement multiplier applied to the United States (Verdery AM, et al.)
- American Psychological Association (APA) (2021). Stress in America: One Year Later, A New Wave of Pandemic Health Concerns
- Pew Research Center (2020). Many Black and Asian Americans say they have experienced discrimination amid the COVID-19 outbreak
- Centers for Disease Control and Prevention (CDC) (2022). Mental Health, Suicidality, and Connectedness Among High School Students During the COVID-19 Pandemic — Adolescent Behaviors and Experiences Survey, United States, January–June 2021 (MMWR Supplement 71(3))
- World Health Organization (WHO) (2023). Statement on the fifteenth meeting of the IHR (2005) Emergency Committee on the COVID-19 pandemic
- Journal of Anxiety Disorders (peer-reviewed) (2020). Development and initial validation of the COVID Stress Scales (Taylor S, et al.)
- Substance Abuse and Mental Health Services Administration (SAMHSA) (2020). Taking Care of Your Behavioral Health: Tips for Social Distancing, Quarantine, and Isolation During an Infectious Disease Outbreak
- Bulletin of the World Health Organization (peer-reviewed) (2022). Infodemics and health misinformation: a systematic review of reviews (Borges do Nascimento IJ, et al.)
- American Psychologist (peer-reviewed) (2022). Loneliness before and during the COVID-19 pandemic: a systematic review with meta-analysis (Ernst M, et al.)
- The Lancet (peer-reviewed) (2020). The psychological impact of quarantine and how to reduce it: rapid review of the evidence (Brooks SK, et al.)
- National Child Traumatic Stress Network (NCTSN) (2021). Parent/Caregiver Guide to Helping Families Cope With the Coronavirus Disease 2019 (COVID-19)
- OMEGA – Journal of Death and Dying (peer-reviewed) (2025). The Effect of the COVID-19 Pandemic on Grief Experiences of Bereaved Relatives: An Overview Review (van Schaik T, et al.)
- OMEGA – Journal of Death and Dying (peer-reviewed) (2022). How do Funeral Practices Impact Bereaved Relatives’ Mental Health, Grief and Bereavement? A Mixed Methods Review with Implications for COVID-19 (Burrell A, Selman LE)
- Journal of Affective Disorders Reports (peer-reviewed) (2023). DSM-5-TR prolonged grief disorder levels after natural, COVID-19, and unnatural loss during the COVID-19 pandemic (Lenferink LIM, Boelen PA)
- BMJ (peer-reviewed) (2023). Comparison of mental health symptoms before and during the covid-19 pandemic: evidence from a systematic review and meta-analysis of 134 cohorts (Sun Y, et al.)
- Journal of Affective Disorders (peer-reviewed) (2022). A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020 (Robinson E, et al.)
- Journal of Criminal Justice (peer-reviewed) (2021). Domestic violence during the COVID-19 pandemic: evidence from a systematic review and meta-analysis (Piquero AR, et al.)
- World Health Organization (WHO) (2020). A guide to preventing and addressing social stigma associated with COVID-19
- Centers for Disease Control and Prevention (CDC) (2026). Long COVID Signs and Symptoms
- Centers for Disease Control and Prevention (CDC). Managing Stress
- World Health Organization (WHO) (2020). Mental health and psychosocial considerations during the COVID-19 outbreak (interim guidance)
- Substance Abuse and Mental Health Services Administration (SAMHSA) (2025). Disaster Distress Helpline
- Federal Emergency Management Agency (FEMA). Disaster Distress Helpline
- National Domestic Violence Hotline. The National Domestic Violence Hotline
- Office for Victims of Crime (OVC), U.S. Department of Justice. Toll Free, Text, and Online Hotlines
- ThroughLine (Find A Helpline). Find A Helpline
- International Association for Suicide Prevention (IASP). Crisis Centres & Helplines
This guide is for education and self-care. It is not a diagnosis or a substitute for professional care. Please talk to a counselor or clinical provider about your health. Reviewed October 2026.

