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Checkups, hormones & mood

Sometimes low mood or anxiety has a body side too. A checkup is a simple, caring way to look at the whole picture.

⏱ 3 min read📑 10 sections📚 13 sources✅ Reviewed October 2026

By the numbers

Numbers about checkups, hormones and mood.

Hormones

50+hormones have been found in the human body. Mood is one of many things they help control.
5 in 100Americans aged 12 and older have an underactive thyroid (hypothyroidism).
1 in 100Americans aged 12 and older have an overactive thyroid (hyperthyroidism).
7–9 yrsis how long menopause symptoms usually last, according to the NHS, sometimes longer.

Checkups

19–64is the age range in which the USPSTF recommends screening adults for anxiety (2023).
67%of U.S. adults had a dental exam or cleaning in the past year (2025 survey).
3–4top concerns is a good number to bring to a visit, the National Institute on Aging suggests.

Why checkups help your mind

Routine visits can catch body causes of low mood, and mental health belongs there too.

A routine checkup is different from a visit when you are sick. It can include screening tests that find problems early, when they may be easier to treat, plus vaccines and a chance to talk about sleep, food, activity and substance use.

Mental health belongs at checkups too. The U.S. Preventive Services Task Force recommends screening adults for depression, including pregnant and postpartum people and older adults. It also recommends screening adults aged 19 to 64 for anxiety.

Some physical problems, like thyroid changes, can feel like low mood or anxiety. A checkup helps rule them out. Ask your provider which checks are right for you.
📋 What screening meansA few questions, not a test you can fail.
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Mental health screening is usually a short set of questions about how you have been feeling. It helps your provider notice if you might need more support.

Answering honestly is safe and helps you get the right care. A screening is not a diagnosis.
💸 If cost is a worryLow-cost options exist.
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Community health centers may offer lower-cost checkups. In the U.S., dial 211 to find local health services.

For insurance, costs and your rights, see the “Paying for care & your rights” guide.

Getting ready for a visit

A short list and a few notes help you cover what matters most.

Visits can feel rushed. A little preparation helps you remember what you wanted to say, including how you have been feeling.

📝 Prepare a short listPick your top three or four concerns.
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The National Institute on Aging suggests writing down everything you want to talk about, then choosing the three or four that matter most. Start your list about a week before so you can add things you remember.

For a new symptom, note

  • How it affects daily life
  • How often it happens
  • What makes it better or worse
  • When it started
  • Whether it is getting better or worse

Mention changes in appetite, weight, sleep or energy since your last visit.

🗣️ Speaking upBe honest, take notes and say if you feel rushed.
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Tips

  • Ask for an interpreter ahead of time if you need one
  • Be honest, even if you think it isn’t what the doctor wants to hear
  • Bring a friend or family member to help remember and take notes
  • Take notes, or ask the doctor to write down the main points
  • Tell them if you feel rushed, worried or uncomfortable

You can say: “I’ve been feeling low and tired for a while. Could we talk about my mood as well?”

📒 Bring your notesA few weeks of tracking tells a clearer story.
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Simple notes on mood, sleep, energy and (if you have periods) your cycle can help your provider see patterns. Use the “Mood, body & cycle tracker” worksheet below.

If appointments make you anxious

You are not alone, and there are ways to make it easier.

Waiting rooms, tests and being examined can bring up a lot of worry, especially if you have had hard experiences with healthcare before. That worry is understandable.

🧰 Before and duringSmall changes that lower the stress.
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Ideas

  • Ask for a telehealth visit if that is an option
  • Bring something to hold or listen to
  • Book the first appointment of the day to avoid waiting
  • Plan a small treat afterward
  • Tell the receptionist or nurse you feel anxious
🫁 Calming your bodySlow breathing helps in the waiting room.
Read more

Breathing out slowly, a little longer than you breathe in, can help your body settle. The breathing guides in this app have short exercises you can do anywhere.

🤝 Feeling heardYou deserve to be taken seriously.
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If you have had a hard experience with healthcare before, the “When the body speaks” guide has tips on working with doctors and feeling heard.

You can ask for a different provider, or bring someone to speak up with you.

Dentist, eyes and ears

The rest of your body’s maintenance counts too.

Dental problems are more common with depression and anxiety, so dental visits are part of caring for your mind. About two in three U.S. adults had a dental exam or cleaning in the past year.

🦷 Dental careMental health and dental health are linked.
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A review of 26 studies covering more than 334,000 people found more tooth decay and tooth loss among people with depression and anxiety.

For brushing on hard days and dental anxiety tips, see the “Washing, dressing & a calmer space” guide.
👓 Eyes and earsStruggling to see or hear can be tiring and isolating.
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Poor eyesight or hearing can make socialising tiring and isolating. Ask your provider how often you should have dental, eye and hearing checks.

Use the “My checkup calendar” worksheet to keep track.

How hormones affect mood

Chemical messengers that can turn feelings up or down.

Hormones are chemical messengers. They travel through your blood and tell your organs what to do and when. Scientists have found over 50 of them, and mood is one of the many things they help control.

Even small changes in hormone levels can have big effects on the body. That is why big hormone shifts in life can come with big feelings. These feelings are real, and they are not a weakness.

🧩 One piece of the pictureHormones work alongside sleep, stress and support.
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Mood is shaped by many things at once: hormones, sleep, stress, relationships, health and life events. A hormone change is rarely the only cause of how you feel.

🔬 Only a test can tellSymptoms alone don’t show what’s going on.
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Many hormone-related symptoms overlap with other conditions. Doctors use blood tests, not symptoms alone, to check things like your thyroid.

Be wary of online quizzes or products that claim to “balance your hormones.” Only a qualified professional can check what is going on.

Hormones through life

Puberty, periods, pregnancy and menopause, in plain words.

Some of the biggest hormone shifts happen at predictable times of life. Knowing what is common can make big feelings less frightening.

🌱 PubertyA body and brain growing fast can bring big emotions.
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Puberty normally starts any time between about 8 and 14 years old. During these years, hormones bring changes in body shape, skin, hair, sweat and feelings.

What many young people notice

  • Feeling more self-conscious about their body
  • Moods that change quickly
  • Needing more sleep
  • New hygiene needs, like deodorant and washing face and hair more often
  • Stronger feelings about friends and fitting in
Ups and downs are common. But if a young person seems low, anxious or withdrawn for weeks, or talks about hurting themselves, reach out to a provider. See the “Teens’ mental health” guide.
🗓️ The menstrual cycleMood can rise and fall with the cycle.
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Hormones rise and fall across the monthly cycle. Many people who have periods notice they feel more tearful, tense, irritable or tired in the days before their period, then better once it starts.

For a smaller group, these changes are severe and get in the way of daily life. The “Periods, PMDD & hormones” guide explains PMS and PMDD in detail.

Tracking your mood alongside your cycle for two or three months can show whether low days follow a pattern. Use the “Mood, body & cycle tracker” worksheet below.
🤱 Pregnancy and after birthHormone changes are one of several things that affect mood.
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Many new mothers have the “baby blues,” mild mood changes in the first two weeks after birth. Mood changes or anxiety that are severe or last longer than two weeks may be a sign of postpartum depression.

Hormone changes during and after pregnancy are one factor, along with sleep loss, stress and support. There is no single cause, and it is never the parent’s fault.

Partners, family and friends are often the first to notice. For much more, see the “Pregnancy & after birth” guide.
🍂 Perimenopause and menopauseMood swings, anxiety and brain fog are common in midlife.
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Menopause means not having had a period for 12 months. In the years around it, many people notice mood swings, low mood, anxiety, and trouble with memory and concentration (“brain fog”). Poor sleep can add to irritability and stress.

The NHS says symptoms usually last 7 to 9 years, sometimes longer, and can change over time. You don’t have to just push through it.

For treatment choices, consult with your clinical provider. See the “Perimenopause & menopause: understanding it” guide for much more.

Thyroid and mood

An underactive or overactive thyroid can affect mood and energy.

Your thyroid is a small gland in your neck that helps set your body’s pace. Nearly 5 in 100 Americans aged 12 and older have an underactive thyroid, and about 1 in 100 have an overactive one.

🐢 Underactive thyroidCan bring tiredness and low mood.
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An underactive thyroid (hypothyroidism) can cause tiredness and depression, along with feeling cold and gaining weight. Many cases are mild and cause few noticeable signs.

🐇 Overactive thyroidCan feel a lot like anxiety.
Read more

An overactive thyroid (hyperthyroidism) can cause nervousness, irritability, trouble sleeping, tiredness and a fast or irregular heartbeat.

👩 Who is more likelyWomen and people over 60.
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Both underactive and overactive thyroid are more common in women and in people over 60.

🩸 How it’s checkedA simple blood test.
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Because these symptoms overlap with other conditions, doctors don’t diagnose thyroid problems from symptoms alone. A simple blood test helps.

If you have new low mood, anxiety or exhaustion, it is reasonable to ask your provider, “Could we check my thyroid?”

Testosterone and age

Low levels can come with low mood and poor focus.

Testosterone levels naturally drop with age, about 1% a year from the late 30s. Cleveland Clinic lists depressed mood and trouble with concentration and memory among the possible symptoms of low testosterone.

🗣️ Raising it with a providerMen often don’t talk about this.
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If you notice low energy, low mood and less interest in things, it is worth raising with your provider. Only a test can show your levels, and other causes need ruling out too.

See the “Men’s mental health” guide too.
🧭 Not the whole storySleep, stress and mood matter too.
Read more

Low energy and low mood in midlife can come from many things, including poor sleep, stress, depression and other health problems. Looking at the whole picture with your provider is the best first step.

For any treatment choice, consult with your clinical provider.

When and where to get help

Signs it is time to book a visit, and where to turn in a crisis.

Book a visit with your clinical provider if

  • Low mood, anxiety or exhaustion last more than two weeks
  • You have new physical symptoms alongside mood changes
  • You notice big changes in sleep, appetite or weight
  • Your mood shifts strongly with your cycle, pregnancy or menopause
  • You haven’t had a checkup in a long time
Having some of these experiences doesn’t mean something is wrong with your hormones. Bodies are complex, and only a qualified professional can check what is going on.

In the U.S., dial 211 to find low-cost health services near you. Outside the U.S., findahelpline.com lists free, confidential helplines in many countries.

If you’re in crisis, call or text 988 (U.S.), or text HOME to 741741. If a life is in danger, call 911.

📝 Worksheets for this guide

Fill these in privately in the app. Your answers stay on your phone.

Checkup prepGet ready for a checkup so you can cover what matters most, including your mood.
Mood, body & cycle trackerNotice how your mood links with your body: sleep, energy, your cycle or other changes. Helpful to bring to a checkup.
My checkup calendarKeep track of when your checkups are due, so caring for your body doesn’t slip.
🔒 Fill in privately in the Mentally United Wellness App. Free, no ads, no accounts.

Sources

  1. MedlinePlus (U.S. National Library of Medicine, NIH). Health Checkup
  2. U.S. Preventive Services Task Force (USPSTF) (2023). Screening for Depression and Suicide Risk in Adults (recommendation)
  3. U.S. Preventive Services Task Force (USPSTF) (2023). Anxiety Disorders in Adults: Screening (recommendation)
  4. National Institute on Aging (NIA), NIH. How To Prepare for a Doctor’s Appointment
  5. Kisely S. et al., peer-reviewed study (2016). The oral health of people with anxiety and depressive disorders: a systematic review and meta-analysis (Journal of Affective Disorders; 26 studies, 334,503 people)
  6. National Center for Health Statistics (NCHS), CDC. FastStats: Oral and Dental Health
  7. Cleveland Clinic. Hormones: What They Are, Function & Types
  8. NHS (UK National Health Service). Early or delayed puberty
  9. National Institute of Mental Health (NIMH). Perinatal Depression
  10. NHS (UK National Health Service). Menopause: symptoms
  11. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH. Hypothyroidism (Underactive Thyroid)
  12. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH. Hyperthyroidism (Overactive Thyroid)
  13. Cleveland Clinic. Low Testosterone (Male Hypogonadism)

This guide is for education and self-care. It is not a diagnosis or a substitute for professional care. Please talk to a counselor or clinical provider about your health. Reviewed October 2026.

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